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Additional file 7: of Deficiency of the BMP Type I receptor ALK3 partly protects mice from anemia of inflammation
figure
posted on 2018-02-27, 05:00 authored by Inka Gallitz, Niklas Lofruthe, Lisa Traeger, Nicole Bäumer, Verena Hoerr, Cornelius Faber, Tanja Kuhlmann, Carsten Müller-Tidow, Andrea SteinbickerSpleen and duodenum mRNA levels in Alk3fl/fl and Alk3fl/fl;Alb-Cre mice 14 days after BA challenge. (a) Relative splenic ferroportin mRNA levels from Alk3fl/fl and Alk3fl/fl; Alb-Cre 14 days after heat-killed Brucella abortus (BA) injection (*P = 0.02: Alk3fl/fl injected with saline [n = 4] vs Alk3fl/fl injected with BA [n = 5]; *P = 0.03: Alk3fl/fl; Alb-Cre injected with saline [n = 4] vs Alk3fl/fl; Alb-Cre injected with BA [n = 4]. (b) Relative splenic TfR1 mRNA levels (*P = 0.01: Alk3fl/fl injected with saline [n = 4] vs Alk3fl/fl injected with BA [n = 6]). (c) Relative duodenal ferroportin mRNA levels. The relative CT method was used to normalize the levels of target transcripts to 18S rRNA levels. (TIFF 103 kb)
