Additional file 7: of Activation of IGF1R/p110β/AKT/mTOR confers resistance to α-specific PI3K inhibition

is a figure showing that p110β activation does not correlate with loss of PTEN. Immunoblots of lysates from parental and resistant cells treated for 24 hours as indicated. BYL719 (IC90) and AEW541 (1 μM). (PDF 140 kb)