Additional file 7: of Activation of IGF1R/p110β/AKT/mTOR confers resistance to α-specific PI3K inhibition

Leroy, Cedric; Ramos, Pedro; Cornille, Karen; Bonenfant, Debora; Fritsch, Christine; Voshol, Hans; Bentires-Alj, Mohamed

doi:10.6084/m9.figshare.c.3629294_D2.v1

13058_2016_697_MOESM7_ESM.pdf (140.8 kB)

Additional file 7: of Activation of IGF1R/p110β/AKT/mTOR confers resistance to α-specific PI3K inhibition

journal contribution

posted on 2016-04-05, 05:00 authored by Cedric Leroy, Pedro Ramos, Karen Cornille, Debora Bonenfant, Christine Fritsch, Hans Voshol, Mohamed Bentires-Alj

is a figure showing that p110β activation does not correlate with loss of PTEN. Immunoblots of lysates from parental and resistant cells treated for 24 hours as indicated. BYL719 (IC90) and AEW541 (1 μM). (PDF 140 kb)