Additional file 7: of A structural preview of aquaporin 8 via homology modeling of seven vertebrate isoforms

Figure S5. Modeling process. Data presented in sharp edged parallelograms and processes with round edged shapes. Each of seven vertebrate AQP8s was modelled twice, using AtTIP2;1 and EcAqpZ as template. Resulting model pairs were hybridized and further refined. Based on the final monomeric model a tetrameric model was formed for HsAQP8, and its stability was studied in MD simulations. (TIFF 118 kb)