12864_2017_3914_MOESM7_ESM.pdf (26.35 kB)
Additional file 7: Table S3. of Development of pathogenicity predictors specific for variants that do not comply with clinical guidelines for the use of computational evidence
journal contribution
posted on 2017-08-11, 05:00 authored by Elena Campa, NatĂ lia Padilla, Xavier CruzPrediction performance for the PRDIS specific predictors in this work for VS2168 dataset; each corresponds to a different combination of the reference predictors (SIFT, PolyPhen-2, PON-P2, CADD and MutationTaster2). The performance measures are the six standard measures (MCC, accuracy, sensitivity, specificity, PPV and NPV) described in the Materials and Methods section. We also give: the total number and the percentage of cases, and the raw TP, TN, FP and FN values. (PDF 26 kb)