13046_2018_671_MOESM7_ESM.pptx (183.94 kB)
Additional file 7: Figure S7. of Anti-tumor effects of ONC201 in combination with VEGF-inhibitors significantly impacts colorectal cancer growth and survival in vivo through complementary non-overlapping mechanisms
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posted on 2018-01-22, 05:00 authored by Jessica Wagner, C. Leah Kline, Lanlan Zhou, Vladimir Khazak, Wafik El-DeiryCD31 expression in HT29 xenografts. Representative IHC staining of CD31 expression from mice treated with indicated drugs. Tumors harvested and placed in paraffin. ONC201: 50 mg/kg every week. Bevacizumab: 5 mg/kg every other week. N=5 tumors, minimum of 3 sections per tumor stained. (PPTX 184Â kb)