12885_2016_2596_MOESM7_ESM.pptx (303.76 kB)
Additional file 7: Figure S3. of Transcriptome analysis of paired primary colorectal carcinoma and liver metastases reveals fusion transcripts and similar gene expression profiles in primary carcinoma and liver metastases
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posted on 2016-07-26, 05:00 authored by Ja-Rang Lee, Chae Kwon, Yuri Choi, Hye Park, Hyun Kim, Hong-Jae Jo, Nahmgun Oh, Do ParkFusion transcripts in validation sets. (A) Gene fusion between ZMYND8 and SEPT9 gene by interchromosomal complex. (B) Gene fusion between ACE2 and PIR gene by intrachromosomal complex. Fusion junction was red arrow, and validation of fusion transcript by RT-PCR and Sanger sequencing in patient #3. Prediction of fusion protein was analyzed by conserved domain database.