12967_2020_2302_MOESM6_ESM.tif (3.55 MB)

Additional file 6 of Trehalose alleviates the phenotype of Machado–Joseph disease mouse models

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posted on 2020-04-10, 03:53 authored by Magda M. Santana, Susana Paixão, Janete Cunha-Santos, Teresa Pereira Silva, Allyson Trevino-Garcia, Laetitia S. Gaspar, Clévio Nóbrega, Rui Jorge Nobre, Cláudia Cavadas, Hagar Greif, Luís Pereira de Almeida

Additional file 6: Fig. S6. Mutant ataxin-3 levels in striatal lentiviral-based model of MJD treated with 2% Trehalose.

Funding

Bioblast Pharma National Ataxia Foundation EU Joint Programme – Neurodegenerative Disease Research Richard Chin and Lily Lock Machado Joseph Disease Research Fund BrainHealth2020 European Regional Development Fund through the Regional Operational Program Center 2020

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Keywords

Machado-Joseph disease Spinocerebellar ataxia type 3 Polyglutamine disorder Trehalose Autophagy

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CC BY + CC0

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