Springer Nature
Browse
13024_2019_335_MOESM6_ESM.tif (103.73 MB)

Additional file 6: of Microglia affect α-synuclein cell-to-cell transfer in a mouse model of Parkinson’s disease

Download (103.73 MB)
figure
posted on 2019-08-17, 04:26 authored by Sonia George, Nolwen Rey, Trevor Tyson, Corinne Esquibel, Lindsay Meyerdirk, Emily Schulz, Steven Pierce, Amanda Burmeister, Zachary Madaj, Jennifer Steiner, Martha Escobar Galvis, Lena Brundin, Patrik Brundin
Figure S6. Example of tissue dissection and nigral cytokine profiling. a Fresh striatal tissue separating the graft (G) from the ipsilateral (Ipsi) and contralateral (Contra) striatum for cytokine profiling and western blotting. The graft tissue was cut in the shape of a rectangle using a blade to separate it from the striatum. b Nigral cytokine profiling within the contralateral and ipsilateral SN using the MesoScale assay on control (blue), LPS-injected (red), and IL-4-injected (orange) mice, ** = p < 0.01. Control, n = 8–10; LPS, n = 8; IL-4, n = 10–12; Str; striatum, error bars represent S.E.M. (TIF 106222 kb)

Funding

National Institutes of Health

History