Additional file 6: of Intrabodies against the Polysialyltransferases ST8SiaII and ST8SiaIV inhibit Polysialylation of NCAM in rhabdomyosarcoma tumor cells

Tumor growth tracking of rhabdyomasarcoma cells expressing the empty vector pCMV/myc/ER (A) or the anti-ST8SiaII-IB and anti-ST8SiaIV-IB (B) in mice over a period of six weeks. 106 rhabdomyosarcoma cells in 100 μl PBS as negative control stable transfected with the empty vector pCMV/myc/ER (A) or expressing anti-ST8SiaII-IB and anti-ST8SiaIV-IB (B) were injected intraperitoneally into 3 C57BL/6 J RAG-2 mice at a time. Luminiscence was determined at week 1 to 6 using in vivo imaging systems (IVIS). Li = Luminiscence intensity. (TIF 960 kb)