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Additional file 6: of CDC42 controls the activation of primordial follicles by regulating PI3K signaling in mouse oocytes

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posted on 2018-07-05, 05:00 authored by Hao Yan, Jiawei Zhang, Jia Wen, Yibo Wang, Wanbao Niu, Zhen Teng, Tongtong Zhao, Yanli Dai, Yan Zhang, Chao Wang, Yingying Qin, Guoliang Xia, Hua Zhang
Figure S6. The survival and development of ovarian follicles were not affected by CDC42 activator treatment. Ovaries were collected at 6 dpp and cultured with or without CDC42 activator for 30 min then transplanted under kidney capsules of ovariectomized adult hosts. After 2 weeks of transplantation, the number of total oocytes in ovaries was quantified. CDC42 activator-treated ovaries showed a comparable number of total oocytes compared to the control (Additional file 10: Individual data values). (PDF 464 kb)

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National Key Research & Developmental Program of China

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    BMC Biology

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    CDC42PI3K signalingPrimordial follicle activationIn vitro activationPremature ovarian insufficiency

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