Springer Nature
Browse
13287_2018_1076_MOESM5_ESM.pdf (462.98 kB)

Additional file 5: of Non-invasive imaging reveals conditions that impact distribution and persistence of cells after in vivo administration

Download (462.98 kB)
journal contribution
posted on 2018-11-28, 05:00 authored by Lauren Scarfe, Arthur Taylor, Jack Sharkey, Rachel Harwood, Michael Barrow, Joan Comenge, Lydia Beeken, Cai Astley, Ilaria Santeramo, Claire Hutchinson, Lorenzo Ressel, Jon Smythe, Eric Austin, Raphael Levy, Matthew Rosseinsky, Dave Adams, Harish Poptani, Brian Park, Patricia Murray, Bettina Wilm
Placement of a region of interest (ROI) for the calculation of relaxation time in the kidney’s cortex. (a) In vivo T2*-weighted image of a single kidney post administration of SPION-labelled mMSCs, (b) placement of an ROI (yellow line) covering the cortex of the kidney where cell/SPION contrast is observed and (c) the changes in signal intensity as a function of echo time, with the solid line displaying the exponential fit of the data, from where the relaxation time is derived. Relaxation times were calculated with Paravision 6.0.1. (PDF 462 kb)

Funding

Medical Research Council

History