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Additional file 5: of M6A-mediated upregulation of LINC00958 increases lipogenesis and acts as a nanotherapeutic target in hepatocellular carcinoma

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posted on 2020-01-09, 05:48 authored by Xueliang Zuo, Zhiqiang Chen, Wen Gao, Yao Zhang, Jinguo Wang, Junfeng Wang, Ming Cao, Juan Cai, Jindao Wu, Xuehao Wang
Figure S2. LINC00958 overexpression facilitates HCC proliferation, migration, and invasion in vitro. (A) Lentiviruses were used to upregulate the expression of LINC00958 in Hep3B and HepG2 cells. (B) CCK-8 assays were performed to assess the cell proliferation in LINC00958-overexpressed Hep3B and HepG2 cells. (C) Colony formation assays showed the clone numbers in HCC cells with LINC00958 overexpression. (D) EdU assays were performed to assess the proliferative ability of Hep3B and HepG2 cells with LINC00958 overexpression. (E) Transwell assays were conducted to examine the effects of LINC00958 overexpression on HCC cell migration and invasion. *P < 0.05, **P < 0.01, ***P < 0.001.

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National Natural Science Foundation of China

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