Additional file 5: of Loss of amphiregulin reduces myoepithelial cell coverage of mammary ducts and alters breast tumor growth

Figure S5 Loss of AREG is associated with increased vascular density in late-stage mammary tumors. (A) Representative images of CD31 staining of AREG+/+ PyMT and AREG−/− PyMT 1-cm tumors. (B) Compared to AREG+/+ PyMT tumors, more CD31+ vessels per field in AREG−/− PyMT tumors. Scale bar shows 100 μm. Statistical analyses performed using a t test. *p < 0.05, N = 3 (PPTX 182 kb)