Additional file 5: Figure S5. of MicroRNA-1296 inhibits metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma by targeting SRPK1-mediated PI3K/AKT pathway

The prognostic significance of miR-1296 and SRPK1 in another cohort of HCC patients. (A) and (B) OS and DFS were compared between miR-1296 high expressing HCC patients and low expressing cases. (C) and (D) OS and DFS were compared between SRPK1 high expressing HCC patients and low expressing cases. (E) and (F) OS and DFS were compared between four subgroups of HCC patients (subgroup I: high miR-1296/low SRPK1; subgroup II: low miR-1296 /low SRPK1; subgroup III: high miR-1296/high SRPK1; subgroup IV: low miR-1296/high SRPK1). For each cohort, subgroups were divided according to the cutoff values, which were determined as the median level of miR-1296 and SRPK1 in HCC tissues. **P < 0.01. (TIFF 213 kb)