Additional file 5: Figure S4. of High-fat feeding rather than obesity drives taxonomical and functional changes in the gut microbiota in mice

Relative abundance of top 5 genera in relation to mouse strain and diet. In mice fed the HF diet, the abundance of Bacteroides decreased, whereas the abundance of Clostridium, Roseburia, and Lactobacillus increased. Irrespective of feed, Bacteroides, Clostridium and Roseburia were more abundant Sv129 mice than in BL6 mice, whereas the relative abundance of Akkermansia was higher in BL6 mice than in Sv129 mice. The statistical differences were analyzed by unpaired Wilcoxon Rank-Sum test (with FDR correction). Statistically significant differences (P < 0.05) between groups are denoted with different letters (a, b, c, d) on the top of the graphic boxes. (PDF 898 kb)