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Additional file 4: of Therapeutic glucocorticoids prevent bone loss but drive muscle wasting when administered in chronic polyarthritis

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posted on 2019-08-02, 07:08 authored by C. Fenton, J. Webster, C. Martin, S. Fareed, C. Wehmeyer, H. Mackie, R. Jones, A. Seabright, J. Lewis, Y. Lai, C. Goodyear, S. W Jones, M. Cooper, G. Lavery, R. Langen, K. Raza, R. Hardy
Figure S3. (a-p) Gene expression of Foxo1, Fbxo32, Trim63, Ube3a, Igf1, Igf2, Mstn, Redd1, Myog, MyoD, Myf5, Myf6, Tnfa, Il6, Cxcl1 and IkBa were determined by RT qPCR in quadriceps for either WT mice and TNF-Tg animals receiving either vehicle or corticosterone (100 μg/mL) in drinking water over 3 weeks. Values are expressed as mean ± standard error of six animals or primary cultures derived from four separate animals. Statistical significance was determined using two-way ANOVA with a Tukey post hoc analysis. *P < 0.05, **P < 0.005, ***P < 0.001. (TIF 1454 kb)

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