13071_2020_4000_MOESM4_ESM.pptx (7.8 MB)
Additional file 4 of The antischistosomal potential of GSK-J4, an H3K27 demethylase inhibitor: insights from molecular modeling, transcriptomics and in vitro assays
presentation
posted on 2020-03-17, 04:39 authored by Jessica Lobo-Silva, Fernanda J. Cabral, Murilo S. Amaral, Patrícia A. Miyasato, Rafaela Paula de Freitas, Adriana S. A. Pereira, Mariana I. Khouri, Mayra M. F. Barbosa, Pablo I. P. Ramos, Luciana C. C. Leite, Oluwatoyin A. Asojo, Eliana Nakano, Sergio Verjovski-Almeida, Leonardo P. FariasAdditional file 4: Figure S4. Decrease in egg size and oviposition in S. mansoni couples exposed to GSK-J4 and GSK-J5 for 72 h. Data are expressed as mean ± SEM from one experiment, data for 30 µM GSK-J5 point was replotted from the previous assay (Fig. 2c) for comparison. *P < 0.05, **P < 0.01 and ***P < 0.001.