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Additional file 4 of Micro-RNA-186-5p inhibition attenuates proliferation, anchorage independent growth and invasion in metastatic prostate cancer cells

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posted on 2018-04-13, 05:00 authored by Dominique Jones, M. Schmidt, Suman Suman, Katharine Hobbing, Shirish Barve, Leila Gobejishvili, Guy Brock, Carolyn Klinge, Shesh Rai, Jong Park, Geoffrey Clark, Rajesh Agarwal, LaCreis Kidd
Table S3. Aberrant gene expression in miR-186-5p inhibited PC-3 and miR-186-5p overexpressing RWPE1 cells. Microarray gene list was restricted to genes down-regulated in RWPE1 (fold change ≤ − 1.2) and up-regulated in PC-3 cells (fold change ≥1.2). Analysis revealed a down-regulation of 493 transcripts in RWPE1 cells and up-regulation of 547 transcripts in PC-3 cells. Genes in bold represent previously validated miR-186-5p targets. Moreover, genes were highlighted gray if modified in both RWPE1 with ectopic expression of miR-186-5p and miR-186-5p inhibited PC-3 cells. (DOCX 81 kb)

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National Cancer Institute

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