Additional file 4: of MiR-362-5p promotes the malignancy of chronic myelocytic leukaemia via down-regulation of GADD45α

Inhibition of miR-362-5p reduced the colony formation ability of CML cell lines. BV173 and K562 cells were transfected with either a miR-362-5p inhibitor (inhibitor) or a miR-362-5p inhibitor control (inhibitor-ctrl). (A&B) Representative micrographs (left) and (B) quantification (right) of colony formation determined with an in vitro anchorage-independent growth assay. Colonies > 0.1 mm were scored. **P < 0.01. (DOC 110 kb)