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Additional file 4: of Loss of amphiregulin reduces myoepithelial cell coverage of mammary ducts and alters breast tumor growth
presentation
posted on 2018-10-26, 05:00 authored by Serena Mao, Minji Park, Ramon Cabrera, John Christin, George Karagiannis, Maja Oktay, Dietmar Zaiss, Scott Abrams, Wenjun Guo, John Condeelis, Paraic Kenny, Jeffrey SegallFigure S4 Necrosis reduced in solid areas of AREG−/− PyMT tumors. Percentage necrosis in solid and papillary areas of AREG+/+ PyMT (N = 32) and AREG−/− PyMT (N = 22) tumors assessed individually. Significant differences observed between solid areas of AREG+/+ PyMT and AREG−/− PyMT tumors. In addition, papillary regions of both tumor genotypes have little to no necrosis. Statistical analysis performed using Mann–Whitney test. *p < 0.05, ***p < 0.001, ****P < 0.0001. n.s. not significant (PPTX 61 kb)
