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Additional file 4 of Influenza vaccination in early Alzheimer’s disease rescues amyloidosis and ameliorates cognitive deficits in APP/PS1 mice by inhibiting regulatory T cells
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posted on 2020-02-20, 05:29 authored by Yunjie Yang, Zitian He, Zhiwei Xing, Zejie Zuo, Lifang Yuan, Yingying Wu, Mei Jiang, Fangfang Qi, Zhibin YaoAdditional file 4: Figure S4. ATRA treatment did not significantly affect CD8+ T cells in IIV-treated APP/PS1 mice. Quantitative analysis of the frequencies of CD8+ T cells in the spleen of ATRA-treated AD+IIV mice by flow cytometry showed no significant effect of the ATRA treatment on the proportions of CD8+ T cells in the spleen of AD+IIV mice (n > 4, mean ± SEM, one-way ANOVA and LSD post hoc test).