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Additional file 4: of GSK3β regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer

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posted on 2019-03-07, 05:00 authored by Geraldine Vijay, Na Zhao, Petra Hollander, Mike Toneff, Robiya Joseph, Mika Pietila, Joseph Taube, Tapasree Sarkar, Esmeralda Ramirez-Pena, Steven Werden, Maryam Shariati, Ruli Gao, Mary Sobieski, Clifford Stephan, Nathalie Sphyris, Noayuki Miura, Peter Davies, Jeffrey Chang, Rama Soundararajan, Jeffrey Rosen, Sendurai Mani
Figure S2. The drugs that were selected from the screen were validated using FACS. The MDA MB 231 reporter cells were treated with all the 11 drugs selected from the screen. Following treatment, the percentage of cells fluorescing red and green were assessed using flow cytometry and plotted for each of the three concentrations to generate the graphs. (PDF 160 kb)

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National Institutes of Health and National Cancer Institute

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    Breast Cancer Research

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    Keywords

    Triple-negative breast cancer (TNBC)Epithelial-mesenchymal transition (EMT)Cancer stem cells (CSCs)Glycogen synthase kinase β (GSK3β)Wnt signaling

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