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Additional file 4: of [18F]FSPG-PET reveals increased cystine/glutamate antiporter (xc-) activity in a mouse model of multiple sclerosis

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posted on 2018-02-22, 05:00 authored by Aileen Hoehne, Michelle James, Israt Alam, John Ronald, Bernadette Schneider, Aloma D’Souza, Timothy Witney, Lauren Andrews, Haley Cropper, Deepak Behera, Gayatri Gowrishankar, Zhaoqing Ding, Tony Wyss-Coray, Frederick Chin, Sandip Biswal, Sanjiv Gambhir
Adjacent coronal brain PET/CT images of a representative EAE mouse. Images of EAE mouse (score 1.5) were acquired ~ 75 min after injection of [18F]FSPG. Images are arranged beginning with caudal slices through to more rostral regions of the brain. Dotted lines highlight region of [18F]FSPG accumulation in meninges and/or in possible meningeal vessel(s) or subarachnoid space. (DOCX 2608 kb)

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