Additional file 4: Figure S4. of Identification and classification of small molecule kinases: insights into substrate recognition and specificity

A model of Kdo kinase (swissprot identifier: KDKA_PASPI) using Rio kinase (pdbid 1zp9) as a template. The residues that show up as contrastingly conserved are shown as blue sticks. As can be seen from the model, characteristic residues cluster together near the putative substrate binding region. The two arginines within the substrate binding region may bind Kdo similar to the twin-arg motif in MTRK (see Fig. 4). (PNG 208 kb)