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Additional file 4: Figure S3. of CD274 promotes cell cycle entry of leukemia-initiating cells through JNK/Cyclin D2 signaling

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posted on 2016-11-17, 05:00 authored by Xia Fang, Chiqi Chen, Fangzhen Xia, Zhuo Yu, Yaping Zhang, Feifei Zhang, Hao Gu, Jiangbo Wan, Xiaocui Zhang, Wei Weng, Cheng Zhang, Guo-Qiang Chen, Aibing Liang, Li Xie, Junke Zheng
CD274 has no effect on the differentiation and apoptosis of LICs. (A) Representative flow cytometric plot for the percentages of Mac-1+/Gr-1+ cells in the recipient mice upon secondary transplantation. (B) Quantification results for panel (A) (n = 3, p > 0.05). (C-E) The apoptotic status was examined by the staining with Annexin V and 7-AAD in WT and CD274-null LICs upon the primary (C-D) or secondary transplantation (E-F) (n = 3, p > 0.05). (PDF 190 kb)

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National Basic Research Program of China

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