13073_2016_340_MOESM4_ESM.pdf (162.91 kB)
Additional file 4: Figure S2. of Cancer network activity associated with therapeutic response and synergism
journal contribution
posted on 2016-08-24, 05:00 authored by Jordi Serra-Musach, Francesca Mateo, Eva Capdevila-Busquets, Gorka de Garibay, Xiaohu Zhang, Raj Guha, Craig Thomas, Judit Grueso, Alberto Villanueva, Samira Jaeger, Holger Heyn, Miguel Vizoso, Hector Pérez, Alex Cordero, Eva Gonzalez-Suarez, Manel Esteller, Gema Moreno-Bueno, Andreas Tjärnberg, Conxi Lázaro, Violeta Serra, Joaquín Arribas, Mikael Benson, Mika Gustafsson, Marc Ferrer, Patrick Aloy, Miquel PujanaCorroboration of CNA-IC50 correlations using a high-quality interactome dataset. The PCC distribution difference between drugs that target CTKs or STKs is maintained when the network is based on a high-quality dataset derived from the combination of reliable literature-curated binary interactions and well-verified high-throughput yeast two-hybrid interactions. (PDF 162 kb)
