Additional file 3: of The dynamics of early-state transcriptional changes and aggregate formation in a Huntington’s disease cell model

Absence of eGFP-Htt-Q23 aggregate formation upon doxycycline induction. PC12 cells expressing eGFP-Htt-Q23 (control) upon doxycycline induction were imaged at various time points post-induction (4 – 120 h) using fluorescence living cell imaging. A-H show the Htt-Q23 eGFP expressing cells at the various post-induction time points (representative examples of at least four replicates per time point). (PPTX 647 kb)