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Additional file 3: of Effect of landiolol on sex-related transcriptomic changes in the myocardium during sepsis

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posted on 2019-08-20, 04:13 authored by Thi Tran, Calypso Mathieu, Magali Torres, Béatrice Loriod, Linh Lê, Catherine Nguyen, Monique Bernard, Marc Leone, Nathalie Lalevée
Table S1. GO annotations for differentially expressed genes in male and female hearts after cecal ligation and puncture. Gene ontology analysis realized with the DAVID Database is reported in the table. The most significant biological processes (BP), cellular components (CC) and KEGG-pathways (KEGG) GO terms for up- and down-regulated genes are indicated for CLP vs sham groups in males and females. For all the processes, the number of genes deregulated in males is much greater than in females. N. of genes = Number of genes; NS = not significant; ø = not found. Table S2. GO annotations for differentially expressed genes in male and female hearts after landiolol administration. Gene ontology analysis realized with the DAVID Database is reported in the table. Significant biological processes (BP) and KEGG-pathway (KEGG) GO terms for up- and down-regulated genes are indicated for CLP plus landiolol vs CLP groups in males and females. For all the processes, the number of genes deregulated in males is much greater than in females and significant biological processes were totally absent for females after landiolol infusion. N. of genes = Number of genes; NS = not significant; ø = not found. (PPTX 51 kb)

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