Additional file 3: of Down-regulation of microsomal prostaglandin E2 synthase-1 in the infrapatellar fat pad of osteoarthritis patients with hypercholesterolemia

Figure S1. Effect of body mass index on cyclooxygenase-2 (COX-2) and microsomal prostaglandin E synthase-1 (mPGES1) expression in synovial tissues (ST) and the infrapatellar fat pad (IPFP). OA patients (n = 145) were divided into three groups (normal, overweight, obese) according to the WHO BMI classification. We examined the expression of COX-2 and mPGES1 in the IPFP and ST using real-time PCR and compared these among normal, overweight, and obese groups. There were no differences in COX-2 or mPGES1 expression in the IPFP or in ST among the groups. GAPDH, glyceraldehyde-3-phosphate dehydrogenase. (TIFF 1428 kb)