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Additional file 3: of Analysis of spinal and muscle pathology in transgenic mice overexpressing wild-type and ALS-linked mutant MATR3

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posted on 2018-12-19, 05:00 authored by Christina Moloney, Sruti Rayaprolu, John Howard, Susan Fromholt, Hilda Brown, Matt Collins, Mariela Cabrera, Colin Duffy, Zoe Siemienski, Dave Miller, David Borchelt, Jada Lewis
Table S2. Average body weights for lead MATR3WT and MATR3F115C lines. MATR3WT mice (lead line 1563) were not significantly different when compared to age-matched NT males (~ 2 mo.: two-way ANOVA, p > 0.05; ~ 10 mo.: t-test, p > 0.05) and females (~ 2 mo.: two-way ANOVA, p > 0.05). At ~ 2 months, MATR3F115C mice (lead line 1576) weighed significantly less compared to age-matched and sex-matched NT mice (two-way ANOVA, p < 0.0001) and at ~ 10 months, male (two-way ANOVA, p < 0.0001) and female (two-way ANOVA, p < 0.05) MATR3F115C mice (lead line 1576) weighed significantly less compared to age- and sex-matched NT mice. Not significant, n.s; *, p ≤ 0.05; ****, p ≤ 0.0001. (DOCX 16 kb)

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National Institute of Neurological Disorders and Stroke

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