Additional file 3: Figure S3 of A brain-targeted, modified neurosin (kallikrein-6) reduces α-synuclein accumulation in a mouse model of multiple system atrophy

Real time PCR analysis of MBP and α-syn expression in MBP-α-syn tg mice. Real-time PCR analysis of gene expression in non-tg and MBP-α-syn tg mouse brain tissue after treatment with LV-Control or LV-NR-R80Q-apoB. Total RNA was extracted and used for real-time PCR analysis using either primers specific for (A) MBP or (B) human α-syn. Gene expression signal was normalized to β-actin signal. n = 4 mice per group. (TIFF 371 kb)