40478_2017_431_MOESM3_ESM.pptx (130.23 kB)
Additional file 3: Figure S2. of Altered Ca2+ homeostasis induces Calpain-Cathepsin axis activation in sporadic Creutzfeldt-Jakob disease
presentation
posted on 2017-04-27, 05:00 authored by Franc Llorens, Katrin Thüne, Beata Sikorska, Matthias Schmitz, Waqas Tahir, Natalia Fernández-Borges, Maria Cramm, Nadine Gotzmann, Margarita Carmona, Nathalie Streichenberger, Uwe Michel, Saima Zafar, Anna-Lena Schuetz, Ashish Rajput, Olivier Andréoletti, Stefan Bonn, Andre Fischer, Pawel Liberski, Juan Torres, Isidre Ferrer, Inga ZerrER stress in the frontal cortex of sCJD cases. ER stress and Ca2+ induced genes in sCJD MM1 by (A) Western-blot (grp78, hsp27, BDNF, Fas and Bcl-2) and (B) Bcl-2/Bax ratio in the frontal cortex of control and sCJD MM1 cases obtained from the densitometric analysis of both proteins detected by western-blot analysis. Unpaired t-test (95% CI) was used for the comparisons of the two groups. *p < 0.05; **p < 0.01; ***p < 0.001. (PPTX 130 kb)
