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Additional file 3: Figure S2. of Aberrant KDM5B expression promotes aggressive breast cancer through MALAT1 overexpression and downregulation of hsa-miR-448

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posted on 2016-02-25, 05:00 authored by Oluwaseun Bamodu, Wen-Chien Huang, Wei-Hwa Lee, Alexander Wu, Liang Wang, Michael Hsiao, Chi-Tai Yeh, Tsu-Yi Chao
KDM5B is preferentially expressed in TNBC tissues. (A) Box plot and (B) Heat map, showing expression of KDM5B and its associated genes in human breast invasive carcinoma. (C) KDM5B overexpression in TNBC is associated with poor prognosis. TCGA data obtained and analysed via UCSC genome browser. (DOCX 312 kb)

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    BMC Cancer

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    hsa-miR-448KDM5BMALAT1Histone demethylaseLong non-coding RNAmicroRNATriple negative breast cancerEpigeneticsAnticancer target

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