Additional file 3: Figure S1. of The dynamics of smoking-related disturbed methylation: a two time-point study of methylation change in smokers, non-smokers and former smokers

Longitudinal regression coefficients for each CpG site under investigation longitudinally, TSQL categories 4–7. The four panels display the coefficients and coefficient p-values for TSQL categories 4 through 7, respectively, for each CpG site under investigation. The longitudinal regression coefficients represent the rate of change of methylation M-value per year relative to never smokers. The results for TSQL categories 1 through 3 are given in Fig. 1. *Statistically significant: the longitudinal coefficient P falls below the Bonferroni-corrected threshold of 8.47e-5. (TIFF 84 kb)