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Additional file 3: Figure S1. of Global analysis of DNA methylation in hepatocellular carcinoma by a liquid hybridization capture-based bisulfite sequencing approach

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posted on 2015-08-21, 05:00 authored by Fei Gao, Huifang Liang, Hanlin Lu, Junwen Wang, Meng Xia, Zhimei Yuan, Yu Yao, Tong Wang, Xiaolong Tan, Arian Laurence, Hua Xu, Jingjing Yu, Wei Xiao, Wei Chen, Ming Zhou, Xiuqing Zhang, Qian Chen, Xiaoping Chen
Tumors are separated from adjacent non-tumors through analysis of the patterns of the promoter methylomes. A, principal component analysis (PCA) of the average methylation levels of total promoters in 8 pairs of HCCs and non-tumor samples; B, cumulative curves of –log(P value) from the chi-square test on intra-group variations of CpG methylation levels in HCC tumors (T) and non-tumors (N).

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