Additional file 2: of Ubiquitin-specific protease 3 promotes cell migration and invasion by interacting with and deubiquitinating SUZ12 in gastric cancer

Figure S1. Functional analysis of USP3 in vitro. (A) Invasive potential of the GC cells transfected with the USP3 or Vector. **, P < 0.05; ****, P < 0.001. (B) (C) & (E) For the wound-healing experiments, cells were analyzed with live-cell microscopy. ****, P < 0.001. (D) Invasive potential of the GC cells transfected with USP3 siRNA or src siRNA. ****, P < 0.001. (F) USP3 is regulated by the AKT/ERK/EMT signaling pathway in GC cells according to the Western blot analysis. (TIF 808 kb)