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Additional file 2: of Therapeutic efficacy, pharmacokinetic profiles, and toxicological activities of humanized antibody-drug conjugate Zt/g4-MMAE targeting RON receptor tyrosine kinase for cancer therapy

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posted on 2019-03-14, 05:00 authored by Hang-Ping Yao, Liang Feng, Sreedhar Suthe, Ling-Hui Chen, Tian-Hao Weng, Chen-Yu Hu, Eun Jun, Zhi-Gang Wu, Wei-Lin Wang, Song Kim, Xiang-Min Tong, Ming-Hai Wang
Tables S1. Pathological and Biological Features of Primary PDAC Cell Lines from Patient-Derived Xenograft Tumors*. Table S2. Adverse Effects of H-Zt/g4-MMAE on blood leukocyte and erythrocytes in Cynomolgus monkey. Table S3. Effect of H-Zt/g4-MMAE in vivo on various enzymatic activities in blood samples collected from cynomolgus monkeys. (PDF 663 kb)

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    Pancreatic cancerRON receptor tyrosine kinaseAntibody-rug conjugatesPharmacokineticsXenograft tumor modelTherapeutic efficacyToxicological profiles

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