Additional file 2: of Subchronic exposure to titanium dioxide nanoparticles modifies cardiac structure and performance in spontaneously hypertensive rats

Figure S2. TEM analysis of the alveolar lung parenchyma from a SHR rat seven weeks after intratracheal instillation of TiO2-NPs. Individual or microaggregates of small electrondense NPs are present in the air space (As) as scattered within the alveolar septum in which a type II pneumocyte (PII) is recognized. NPs are also apparent in endothelial cells lining a capillary (*) and the lumen of a larger venule containing red blood cells (RBC) polymorphonuclear (PMN) neutrophils, lymphocytes (Lym) and platelets (arrow). Magnification 1800X. Scale Bar: 10Îźm. (PDF 2011 kb)