12989_2019_311_MOESM2_ESM.pdf (1.96 MB)

Additional file 2: of Subchronic exposure to titanium dioxide nanoparticles modifies cardiac structure and performance in spontaneously hypertensive rats

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journal contribution
posted on 24.06.2019 by Stefano Rossi, Monia Savi, Marta Mazzola, Silvana Pinelli, Rossella Alinovi, Laura Gennaccaro, Alessandra Pagliaro, Viviana Meraviglia, Maricla Galetti, Omar Lozano-Garcia, Alessandra Rossini, Caterina Frati, Angela Falco, Federico Quaini, Leonardo Bocchi, Donatella Stilli, StĂŠphane Lucas, Matteo Goldoni, Emilio Macchi, Antonio Mutti, Michele Miragoli
Figure S2. TEM analysis of the alveolar lung parenchyma from a SHR rat seven weeks after intratracheal instillation of TiO2-NPs. Individual or microaggregates of small electrondense NPs are present in the air space (As) as scattered within the alveolar septum in which a type II pneumocyte (PII) is recognized. NPs are also apparent in endothelial cells lining a capillary (*) and the lumen of a larger venule containing red blood cells (RBC) polymorphonuclear (PMN) neutrophils, lymphocytes (Lym) and platelets (arrow). Magnification 1800X. Scale Bar: 10Îźm. (PDF 2011 kb)


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