12859_2019_3043_MOESM2_ESM.tsv (5.26 kB)

Additional file 2 of SigsPack, a package for cancer mutational signatures

Download (5.26 kB)
posted on 03.09.2019 by Franziska Schumann, Eric Blanc, Clemens Messerschmidt, Thomas Blankenstein, Antonia Busse, Dieter Beule
Exposure estimation for synthetic data example. Exposure estimation from synthetic data. 1000 mutations have been generated at random, using frequencies from set1 (signatures 7, 13, 21, 24 & 28), and set2 (signatures 3, 5, 8, 16, & 25). A perfect reconstruction would have original exposure values very close to 0.2 for these 5 signatures, and 0 for all the others. The mutational catalogues was resampled 1000 times, and for each signature, the minimum, first quartile, median, third quartile and maximum values of exposures computed from the re-sampled data are shown. (TSV 5 kb)


Deutsche Forschungsgemeinschaft