Additional file 2: of Restriction enzyme digestion of host DNA enhances universal detection of parasitic pathogens in blood via targeted amplicon deep sequencing

Figure S2. Scatterplots demonstrating human reads per thousand (x-axis) vs parasite reads per thousand (y-axis) for undigested samples (black), digested samples cleaned using the > 2 kb DNA cleanup protocol (red), and digested samples cleaned using the < 2 kb DNA cleanup protocol (blue). Plots demonstrate a shift in reads for all parasite species tested: (a) P. falciparum, (b) P. vivax, (c) P. ovale, (d) P. malariae, (e) P. knowlesi, (f) B. microti, (g) B. divergens, (h) B. duncani, (i) L. infantum subspecies infantum, (j) L. infantum subspecies donovani, (k) T. cruzi, (l) T. brucei subspecies rhodesiense, (m) B. malayi, (n) W. bancrofti, (o) L. loa, and (p) C. felis. (TIF 5182 kb)