Additional file 2 of PSAT1 is regulated by ATF4 and enhances cell proliferation via the GSK3β/β-catenin/cyclin D1 signaling pathway in ER-negative breast cancer

Gao, Song; Ge, Anqi; Xu, Shouping; You, Zilong; Ning, Shipeng; Zhao, Yashuang; Pang, Da

doi:10.6084/m9.figshare.12038088.v1

13046_2017_648_MOESM2_ESM.pdf (1.28 MB)

Additional file 2 of PSAT1 is regulated by ATF4 and enhances cell proliferation via the GSK3β/β-catenin/cyclin D1 signaling pathway in ER-negative breast cancer

journal contribution

posted on 2020-03-27, 04:18 authored by Song Gao, Anqi Ge, Shouping Xu, Zilong You, Shipeng Ning, Yashuang Zhao, Da Pang

Effects of PSAT1 on the migration, invasion and apoptosis of ER-negative breast cancer cells. (A) Transwell assays were used to investigate changes in cell migration and invasion. **P < 0.01, ***P < 0.001, ****P < 0.0001. (B) Apoptosis assay based on flow cytometry shows that the suppression of PSAT1 increased the proportion of early apoptotic cells. (PDF 84 kb)

Funding

National Natural Science Foundation of China (CN) project of Heilongjiang Province Applied Technology Research and Development National Key Technology Support Programme National Health and Family Planning Commission of the People's Republic of China

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Keywords

PSAT1 Estrogen receptor (ER)Cell cycle GSK3β/β-catenin/cyclin D1 pathway ATF4

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