13045_2016_362_MOESM2_ESM.tif (3.04 MB)
Additional file 2: of Inhibition of bromodomain and extra-terminal (BET) proteins increases NKG2D ligand MICA expression and sensitivity to NK cell-mediated cytotoxicity in multiple myeloma cells: role of cMYC-IRF4-miR-125b interplay
figure
posted on 2016-12-01, 05:00 authored by Maria Pia Abruzzese, Maria Bilotta, Cinzia Fionda, Alessandra Zingoni, Alessandra Soriani, Elisabetta Vulpis, Cristiana Borrelli, Beatrice Zitti, Maria Petrucci, Maria Ricciardi, Rosa Molfetta, Rossella Paolini, Angela Santoni, Marco CippitelliULBPs and Nec-2 ligand expression on SKO-007(J3) cells following treatment with JQ1. ULBPs and Nec-2 surface expression were analyzed by immunofluorescence and flow cytometry on SKO-007(J3) cells treated with JQ1 as described above for 72Â h. The grey-colored histograms represent basal expression of the indicated ligand, while thick black histograms represent the expression after treatment with the drug. Data are representative of three independent experiments. (TIF 3116Â kb)
