13148_2018_471_MOESM2_ESM.pdf (110.33 kB)
Additional file 2: of Identifying and correcting epigenetics measurements for systematic sources of variation
journal contribution
posted on 2018-03-21, 05:00 authored by Flavie Perrier, Alexei Novoloaca, Srikant Ambatipudi, Laura Baglietto, Akram Ghantous, Vittorio Perduca, Myrto Barrdahl, Sophia Harlid, Ken Ong, Alexia Cardona, Silvia Polidoro, Therese Nøst, Kim Overvad, Hanane Omichessan, Martijn Dollé, Christina Bamia, José Huerta, Paolo Vineis, Zdenko Herceg, Isabelle Romieu, Pietro FerrariFigure S2. Quantile-quantile (QQ) plots for CpG site-specific analysis with respect to smoking using standard adjustment (a), residuals (b), ComBat (c) and SVA (d) correcting methods for the β values. The inflation factor λ is defined as the ratio of the median of the observed log10 transformed p values from the CpG site-specific analysis and the median of the expected log10 transformed p values. (PDF 110 kb)
