Additional file 2: of Gut metagenomes of type 2 diabetic patients have characteristic single-nucleotide polymorphism distribution in Bacteroides coprocola

Figure S1. Validation of relative abundance distribution in the T2D and HC groups. Figure S2. Comparisons of SNP densities in 20 gut bacterial species between the T2D and normal groups. Figure S3. Brief flowchart for bioinformatics analysis of metagenomics NGS data at strain level. Figure S4. Distributions of MuAFs at variant sites of B. coprocola in T2D (A), HC (B) and all (C) samples with sufficient NGS reads. Figure S5. Phylogenetic tree of B. coprocola strains based on variant sites with >0.8 MuAFs. Figure S6. Results of AP clustering and hierarchical clustering based on MuAFs of variant sites in B. coprocola. Figure S7. Distributions of MuAFs at variant sites in EDU99824.1 (A) and EDUV02303.1 (B). Figure S8. Results of AP clustering and hierarchical clustering based on MuAFs of variant sites. (PDF 761 kb)