13148_2016_297_MOESM2_ESM.doc (92 kB)
Additional file 2: of Epigenome-wide association data implicates DNA methylation-mediated genetic risk in psoriasis
journal contribution
posted on 2016-12-05, 05:00 authored by Fusheng Zhou, Changbing Shen, Jingkai Xu, Jing Gao, Xiaodong Zheng, Randy Ko, Jinfa Dou, Yuyan Cheng, Caihong Zhu, Shuangjun Xu, Xianfa Tang, Xianbo Zuo, Xianyong Yin, Yong Cui, Liangdan Sun, Lam Tsoi, Yi-Hsiang Hsu, Sen Yang, Xuejun ZhangFigure S1. Genomic annotation for methylation probes. Refseq genes annotations were from the University of California, Santa Cruz (UCSC) hg18 reference genome [National Center for Biotechnology Information (NCBI) Reference Sequence Database Release 37]. CpG sites located in or near Refseq genes are separated into TSS1500 (1500 bp upstream of the transcription start site), TSS200, 5ⲠUTR, first exon, gene body, and 3ⲠUTR regions. Intergenic probes refer to methylation sites not mapping to any of the other categories. The ambiguous regions include sites that fell into two or more different categories. The promoter region includes methylation sites located in TSS1500, TSS200, 5ⲠUTR, and first exon. (DOC 92 kb)