Additional file 2: of Effectors of Th1 and Th17 cells act on astrocytes and augment their neuroinflammatory properties

Clinical course of WT and α4−/− mice. EAE severity was monitored in WT and α4−/− mice following immunization with MOG35–55 in CFA. WT mice showed the signs of classical EAE whereas α4−/− mice had an ataxic EAE syndrome. Data is represented as mean clinical score + SEM (n = 6). (TIFF 419 kb)