Additional file 2: of DNA methylation changes that precede onset of dysplasia in advanced sessile serrated adenomas

Supplementary Figure 1. Methylation of CIMP gene and MLH1 promoters as assessed by the MethylationEPIC array. Each data point represents a promoter-associated probe, plotted as the β value difference between SSAD backgrounds and SSAs (βSSAD backgrounds − βSSAs). A positive value indicates hypermethylation in the SSAD background, and a negative value indicates hypomethylation in the SSAD background. Significantly different probes are highlighted in red. TSS, transcription start site. (DOCX 40 kb)