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Additional file 2 of Cytokine pre-activation of cryopreserved xenogeneic-free human mesenchymal stromal cells enhances resolution and repair following ventilator-induced lung injury potentially via a KGF-dependent mechanism

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posted on 2020-02-06, 04:51 authored by Shahd Horie, Sean Gaynard, Mary Murphy, Frank Barry, Michael Scully, Daniel O’Toole, John Laffey
Additional file 2: Figure S2. Pre-activated, cryopreserved, XF-hMSCs enhance the resolution of alveolar cell counts. Fresh, but not cryopreserved, XF-hMSCs decreased alveolar cell counts, while cytokine pre-activation restored the efficacy of cryopreserved hMSCs in reducing alveolar cell counts. ** and ***P < 0.01 and 0.001, respectively, versus PBS control; $$P < 0.01 versus naive cryopreserved group. Sham, n = ; PBS control, n = 8; fresh, n = 8; fresh pre-activated, n = 7; cryopreserved, n = 5; cryopreserved pre-activated, n = 7.

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H2020 European Research Council

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