Additional file 2: of CD4+ αβ T cell infiltration into the leptomeninges of lumbar dorsal roots contributes to the transition from acute to chronic mechanical allodynia after adult rat tibial nerve injuries

Figure S2. Mapping of αβ T cells along the somatosensory pathways 7 days after adult rat mSNIs or sham surgeries with chromogenic IHC for αβTCR. (A) The infiltration of αβ T cells across the whole course of the L4 DR leptomeninges 7 days after mSNIs and sham operations. (B) The infiltration of αβ T cells in the cell-body-rich areas of L4 DRGs, L4 SC-DHs, the sural nerves, and the hindpaw glabrous sural skins 7 days after mSNIs and sham operations. (C) The infiltration of αβ T cells in the proximal and distal stumps of the injured tibial nerves and the hindpaw glabrous tibial skins 7 days after mSNIs and sham operations. DR: dorsal root; DRG: dorsal root ganglion; LM: leptomeninge; mSNI: modified spared nerve injury; P: parenchyma; SC-DH: spinal cord dorsal horn; TN: tibial nerve. (JPEG 4787 kb)