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Additional file 2: of A human endogenous retrovirus encoded protease potentially cleaves numerous cellular proteins

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posted on 2019-08-23, 04:25 authored by Giuseppe Rigogliuso, Martin Biniossek, John Goodier, Bettina Mayer, Gavin Pereira, Oliver Schilling, Eckart Meese, Jens Mayer
Figure S1. Self-processing of HERV-K(HML-2) Protease during purification. Figure S2. Additional examples of verifications of processing of human proteins by HERV-K(HML-2) Protease in vitro. Figure S3. Additional examples of verifications of processing of human proteins by HERV-K(HML-2) Protease in vivo and documentation of loading controls. Figure S4. Quantification of GFP-positive live cells and exclusion of processed protein products due to caspase activity. Figure S5. Localization of EGFP-Pro-mut in human osteosarcoma U2OS and HEK293T cells. Figure S6. Evidence for presence of HERV-K(HML-2) Protease in cell lines known to express HERV-K(HML-2) at relatively high levels. (PDF 5270 kb)

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